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Inadequate intake, decreased absorption, or increased loss of zinc all can result in zinc deficiency

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Thus, all three of the main UA transporters may contribute to the brain concentrations of UA through their action at the blood-brain barrier, although ABCG2 is thought to have the greatest effect, probably acting to remove UA from brain to blood 45

Those with a Diagnosed Vitamin B12 Deficiency : Individuals who have been tested and found to have low levels of Vitamin B12 will benefit from injections to quickly correct the deficiency

doi: 10.1016/j.addr.2012.10.002