hypothesis glutathione persister cells Drug-tolerant cancer are vulnerable to GPX4 inhibition JCI Insight - Mitochondrial metabolic
JCI Insight Mitochondrial metabolic rewiring sensitizes mTORC1 inhibitor persister cells to cuproptosis Vaccinia related kinase 2 inhibition elicits vulnerability of glutathione metabolism in pancreatic cancer Cell Death & Disease JCI CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione GPX4 Role of Glutathione in Cancer: From Mechanisms to Therapies Persister cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Frontiers Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death
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