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As per EULAR recommendations, anti-CD20 treatment can be tried in refractory SLE patients

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(B) Expression profile of bax and bcl-2 gene was assayed using real-time quantitative RT-PCR

Generated ROS during MTX administration provoke DNA damage and induce apoptosis via activating intrinsic apoptotic pathways, as documented in various studies (Koppelmann et al., 2012

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As shown in Figure 5, meta-analysis demonstrated no statistically significant difference in adverse event incidence between curcumin and placebo groups (OR = 0.03, 95% CI: 0.03 to 0.09