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[57] Additionally, the receptor undergoes unique regulatory processes, including desensitization and internalization that are partly independent of -arrestin, further distinguishing it from other GPCRs and influencing its response to long-term pharmacological modulation

Conclusion In conclusion, we observed that low B 12 status was associated with a significantly increased risk of depressive symptoms over 4-year period in a large population representative study of older adults

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Shin BS, Do YS, Cho HS, Kim DI, Hahm TS, Kim CS, et al