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Pharmacol Rep 62:483493

A deficiency in B12 can contribute to feelings of sadness or depression

The ideal approach depends on individual circumstances

The Akkermansia species muciniphila has been shown to alter glucose and lipid metabolism as well as intestinal immunity 86 , to strengthen the integrity of the enterocyte monolayer to possibly improve intestinal barrier integrity 87 , and to improve glucose tolerance and reduce visceral adipose tissue inflammation in mice fed an HFD 88