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Perfil de pptido Nombre del pptido: IGF-1 LR3 (Factor de crecimiento similar a la insulina-1 Long Arg3)

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Dysregulation of T-type channels has been implicated in several pathophysiological conditions, including pain, atrial fibrillation, epilepsy, hypertension, cancer, and congestive heart failure, although most of these disorders involve multiple contributing factors beyond T-type channel activity [68, 134]

Concurrently, hyperphosphorylation and its abnormal accumulation, coupled with impaired clearance, lead to the formation of NFTs, further compromising neuronal function

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