DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE alcohol 494 Purity (HPLC) >= 95%

494 Purity (HPLC) >= 95% Solubility DMSO

enabling researchers to use both SNAP-tag and CLIP-tag in the same experiment

Product Name DOTA-octyne Synonyms CAS Number n/a Related CAS Molecular Formula C24H41N5O7 Molecular Weight 511

644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

34 Purity (HPLC) >= 95% Physical Appearance Dark Solid Optical Properties Abs/Em Maxima: 652/674 nm Solubility DMSO

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE alcohol 494 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing