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Description

Theranostics 7 , 10361046 (2017)

10.1016/j.bbrc.2021.08.067 55 HeS.LiR.PengY.WangZ.HuangJ.MengH.et al (2022)

They are not drugs, dietary supplements, foods, cosmetics, or medical devices, and they are not approved to diagnose, treat, cure, or prevent any disease or condition

201,202 Administration of the PRMT6 inhibitor EPZO20411 can inhibit the arginine methylation of chromatin condensation regulator 1 (RCC1), block the tyrosine kinase 2 (CK2) -PRMT6-RCC1 signaling axis, inhibit the proliferation of glioblastoma stem cells (GSCs) and increase their sensitivity to radiotherapy