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A specific cluster of proteins was found to have higher abundances in the pre-hepatectomy stage compared to the anhepatic and post-reperfusion stages, and ORA identified genes enriched in pathways involving the complement cascade and its regulation, highlighting the likely key role of complement activation in driving liver damage and fibrosis in cirrhosis

These metabolites directly regulate the activity and specificity of DNA methyltransferases (DNMTs) and ten-eleven translocation (TETs) enzymes through their roles as substrates, cofactors, or competitive inhibitors

elegans worms using the MagMAX-96 for Microarrays Total RNA Isolation Kit (InvitrogenTM Life Technologies, Carlsbad, CA), in an automated fashion using the magnetic particle processors MagMAXTM Express

doi: 10.1523/JNEUROSCI.20-09-03496.2000 124 ScholtensE

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Randomized Block Experimental Designs Can Increase the Power and Reproducibility of Laboratory Animal Experiments