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mGlu5 receptor NAMs are candidate drugs in the treatment of pain associated with PD, because these agents have consistently shown analgesic activity in models of chronic inflammatory and neuropathic pain 179,180

In June 2015, the FDA placed the study on hold for compliance violations that posed unreasonable and significant risk of illness or injury to human subjects, and the university terminated the trial five months later

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Its also present in animal proteins like chicken, fish, and beef