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The intensity of the response was reported to be roughly proportional to the length of exposure time (1 - 60 min) and the concentration (Hollingsworth et al., 1956)

In addition, there are no available biomarkers for NCGS

Consistent with the effects of IGF-1 on longitudinal bone growth, which were quite evident in this study, the LID+ALSKO mice also exhibited significant alterations in the size and mass of bone, as shown by reduced femoral periosteal circumference, smaller cross-sectional area, and a thinner cortex compared with control mice

This finding is consistent with the humoral mediated process seen in the muscle of patients with dermatomyositis, as described earlier

Frantz, R

*Correspondence: Jianqun Lin [email protected] Pang [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers