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[13] Chloramphenicol has been shown to blunt reticulocyte response to cyanocobalamin, while ethanol, colchicine, and nitrous oxide interfere with cobalamin metabolism or utilization, each warranting clinician awareness when evaluating suboptimal treatment outcomes

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During the LIA, increased regional hurricane activity offset drying by supplementing local rainfall, illustrating the critical need to independently assess local hurricane contributions in paleo-hydroclimate reconstructions

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