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Thus, ASD is characterized by an imbalance of the processes of mitochondrial fusion, fission, and mitophagy that leads to contamination of the brain with dysfunctional mitochondrial fragments, insufficient energy supply to the brain tissues, and as a result, impairments of memory and synaptic function [187] contributing to ASD pathogenesis

Resveratrol Sirtuin 1(Sirt1), an NAD-dependent deacetylase, inhibits apoptosis in mammalian cells