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GHK-Cu acts on fibroblasts at the dermal level

doi: 10.1016/j.biopha.2018.02.082

In contrast, decreased expression of mitochondrial ferritin can initiate mitochondrial autophagy through the ROS/PINK1/Parkin pathway, leading to the accumulation of ferritin and the enhancement of ferroptosis in osteoblasts ( Figure 3 ) (135)