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This metabolic pathway is more than just a reversal of glycolysis

The development of post-exertional malaise could in turn, however, lead to a further reduction in exercise capacity in patients, as the acute reduction in mitochondrial SDH activity, occurrence of tissue necrosis, and possibly intramuscular accumulation of amyloid-containing deposits could worsen skeletal muscle metabolism and force production over time, causing a vicious downward circle

Scoliosis is seen in a high percentage of girls, up to 65% (283)

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Retinol, retinal, retinoic acid, and related compounds are known as retinoids