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This loading dose is given as an option to help achieve a target level within days, versus using only the maintenance dose, which reaches the target within months

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Certain proteins function as hormones and signaling molecules, while others help in transport, such as hemoglobin carrying oxygen in the blood

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The LC-MS metabolite peaks were manually identified and integrated by EL-Maven (Version 0.11.0) by matching with a previously established in-house library 99

597 In addition, bioinformatics analysis shows that Nrf2 is the target of FTO, and FTO impairs Nrf2 mRNA stability through an m6A dependent pathway, revealing the potential function of FTO in PD neurological diseases