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Ethical approvals for the use of human material All uses of human material have been approved for this study

Zou B, et al

The cryo-EM maps and coordinates for the GluK2 in the intermediate state, deep-desensitized state 1, deep-desensitized state 2, and deep-desensitized state3 have been deposited in the EMDB under accession numbers EMD-48760, EMD-48759, EMD-48758, and EMD-48757, and in the PDB under accession codes, 9MZL, 9MZK, 9MZJ, and 9MZI, respectively