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Boini, K

When Botox is injected into the penis (into the intracavernosal smooth muscles), it helps block certain nerve signals that normally cause these muscles to tighten

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Consequently, the potency of RG7774 in CHO cells reported by -arrestin recruitment assays (EC 50 99.69 5.72 nM) was lower than that observed in cAMP assays (EC 50 : 2.81 0.28 nM) and was closer to the Ki of 51.3 16.2 nM observed in this cell line

If you still cannot tolerate the maintenance dose of 2.4 mg once weekly, speak with your healthcare professional about decreasing the maintenance dose to 1.7 mg once a week