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Interestingly, sensation to the face typically remains intact

In addition, substitutions were limited to elements with similar electronic orbital characteristics, defined here as having the same dominant valence-orbital types with effectively identical electronic configurations near the band edges without introducing additional strongly correlated d or f states

doi:10.1002/14651858.CD002025.pub5 Santo Jr T, Clark B, Hickman M, et al

CSCs are a population of cells within a tumor that possess the ability to self-renew, evade drug action, and reconstitute a heterogenous tumor (39)