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Captopril, an angiotensin-converting enzyme inhibitor, is widely used in clinical practice to treat hypertension, MI, and congestive heart failure and is effective in attenuating left ventricular (LV) dilatation, ameliorating LV ejection fraction and improving cardiovascular morbidity and mortality [237, 238]

Hepatology 45 , 11181128 (2007)

The tesamorelin + ipamorelin combination solved that by pairing a long-acting GHRH analogue with a selective ghrelin agonist

This maintains receptor sensitivity, allows assessment of results, and reduces risk of side effects from prolonged GH elevation

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the mechanistic pathway is GH-driven IGF-1 elevation promoting myogenesis and lipolysis