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Response: We appreciate the commenters' remarks as to the importance of maintaining the ability of the physician/NPP to make changes to a patient's POC outside of the 10-day window, as noted at 410.61(d), if we were to adopt this 10-day window policy

These lipotropes reduce fat production in the body

Weight loss on tirzepatide must remain gradual and medically supervised to prevent complications such as dehydration or electrolyte imbalance

Regular Movement and Exercise Research has shown that a sedentary lifestyle, sitting too much, and poor physical fitness can increase the risk of blood clotting ( 31 , 32 )