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The table below summarizes the practical differences

The underlying mechanisms are multifactorial and not fully understood, but increasing evidence highlights the gutbrain axis and the intestinal microbiome as critical contributors to disease onset and progression (He et al., 2023

10.1093/carcin/bgq285 99 NewmanE

Network meta-analysis on the effects of finerenone versus SGLT2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in patients with type 2 diabetes mellitus and chronic kidney disease

Ahamed M, Siddiqui MK

However, adding exogenous glutathione or glutathione ethyl ester did not increase cellular glutathione and was therefore not pursued further