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Among them, MMPs are a highly conserved family of endopeptidases, consisting of 28 known members, that depend on zinc and calcium ions

DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function

doi: 10.1002/cpt.1548, 93 NashY.SchmuklerE.TrudlerD.Pinkas-KramarskiR.FrenkelD

Beyond recapitulating established pathways, we dedicate considerable attention to translational implications, systematically evaluating potential therapeutic avenues such as anti-inflammatory modulation, oxidative stress mitigation, and lung microbiota remodeling