slc25a39 glutathione

slc25a39 glutathione Fusion Protein Ag7141 Mitochondrial GSH import is mediated

Name: slc25a39 glutathione Fusion Protein Ag7141 Mitochondrial GSH import is mediated
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SKU: 83540185799
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Mitochondrial GSH import is mediated by SLC25A39 a, Volcano plots Download Scientific Diagram SLC25A39 overexpression exacerbates lung adenocarcinoma progression and is negatively regulated by AFG3L2 npj Precision Oncology How the antioxidant glutathione keeps mitochondria healthy SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells Nature Controlling glutathione entry into mitochondria: potential roles for SLC25A39 in health and (treatment of) disease Signal Transduction and Targeted Therapy SLC25A39 is required for mitochondrial glutathione transport Volcano Download Scientific Diagram

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This mechanism may be attributed to the interference with copper ion transport leading to increased ROS levels, mitochondrial dysfunction and reduced ATP production, ultimately inhibiting Cu/Zn SOD1 activity (136)