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Hakanen, J., Ruiz-Reig, N

Excessive accumulation of ROS against the background of dysregulation of the antioxidant system leads to the oxidation of intracellular proteins, DNA, and lipids, which ultimately leads to disruption of mitochondrial energy

doi: 10.21448/ijsm.559679 69

Pharmaceutics 19 , 21752182 (2022)

Patient adherence and compliance Patient adherence is a critical factor of the effectiveness of KD

LLD is highly prevalent, often underdiagnosed and inadequately treated, associated with variable antidepressant response, disability and increased mortality, and can profoundly diminish quality of life [1,2,3,4,5]