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doi: 10.1016/j.ijbiomac.2016.11.066 7 RansfordRAJLangmanMJS

The activation of target genes and the regulation of phase II detoxification enzymes, antioxidant enzymes, and drug transporters via the Keap1-Nrf2-ARE signalling pathway play crucial roles in mitigating oxidative damage and maintaining cellular homeostasis [96]