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ARG2 is also highly expressed in immunosuppressive cells within the tumor microenvironment, such as DCs (277), Tregs (278), TAMs (277), and cancer-associated fibroblasts (276)

In particular, the presence of CDS variants in genes that regulate or interact with the Hippo signalling pathway ( Par-1 (missense mutation), misshapen (frameshift mutation)), together with the elongated midgut observed in Abx-treated SL flies, suggests that midgut elongation was potentially influenced by these variants (Supplementary Data 11, Figs

Neonatal effects of maternal hypothyroxinemia during early pregnancy

Conventional treatments such as Propylthiouracil (PTU) often exhibit adverse effects, highlighting the need for safer alternatives

significantly, the inhibition of autophagy with bafilomycin abrogated this sensitization, and the CXCR4 antagonist AMD3100 demonstrated a synergistic effect with DOX in vivo