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In db/db T2D-like diabetic mouse islets, the mTOR to AMPK switch is reversed and associated with a loss of oxidative metabolism and de-differentiation of -cells (Jaafar et al., 2019)

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Grace Burton , Stephanie (Robbins) Wadhwani , Whit Cooney , and Grace Potts completed their orientation for the Morrison Healthcare Dietetic Internship

Cholangiocyte organoids can repair bile ducts after transplantation in the human liver

These authors found that toxic IAPP oligomers initially appear within the granules in the secretory pathway, where they disrupt the membranes of the granules, leading to their release into the cytoplasm