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retatrutide in Phase III Metabolic focus: Obesity, overweight, type 2 diabetes, sleep apnea, osteoarthritis, MASLD/MASH and cardiovascular/renal outcomes Eli Lillys obesity portfolio includes Zepbound, the newly approved oral GLP-1 drug Foundayo and the Phase III candidate retatrutide

Microvascular changes in Parkinsons disease- focus on the neurovascular unit

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As seen in Table 4, all of the clinical trials testing MET/HGF-directed therapy alongside chemotherapy assessed MET expression using immunohistochemical (IHC) staining of tumour samples

The BBB employs various transport systems, such as carrier-mediated transport (CMT), receptor-mediated transport (RMT), active efflux transport, vesicular trafficking by transcytosis, and ion transport, to facilitate the entry of essential substances into the brain parenchyma and the efflux of metabolic waste and endogenous neurotoxins [19, 23]