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The resulting vcf file was then filtered using vcftools 53 to retain loci where all six colonies had at least 10 coverage, with a minimum quality score of 30

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Although the included studies were conducted in rodent models, Met has long been (1950s) used clinically for diabetes and shows benefits in improving testosterone levels and sperm parameters in men []

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, VHL deletion) or reactive oxygen species (ROS) under normoxia, compounded by tumor vascular abnormalities inducing regional hypoxia ( Figure 1 )

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