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10.1016/j.jep.2022.115001 J

The reason is, hepatocytes can proliferate continuously, with individual hepatocytes surviving for about three years [63], which may substantially dilute the AAV genome and even lead to loss of transgene expression, subsequently reducing the therapeutic effect

Taxonomic profiling and populational patterns of bacterial bile salt hydrolase (BSH) genes based on worldwide human gut microbiome

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However, our findings also indicate that the effects of AKT-E17K on radiosensitivity of TrC1 cells go beyond its role in regulating glycolytic activity

Pommerening Dornelles E, Gama Marques J, Ouakinin S