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Abnormal glucocorticoid receptor-activator protein 1 interaction in steroid-resistant asthma

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Using digital pathology scores calculated from the % of tissue area with a fluorescent signal above an assigned threshold of MUC1 or HIF-1, we determined that expression of both markers was significantly higher in patients who experienced recurrence 3 years after their initial diagnosis (Fig

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This epigenetic intervention engages in extensive cross-talk, potentially through global demethylation and modulation of microRNA expression, thereby reversing aberrant gene transcription profiles in cancer (65)

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