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In the cytosol, reducing conditions favor SERCA glutathionylation and an increase in activity (Qin et al., 2013

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CrossRef Interplay of skeletal muscle and adipose tissue: sarcopenic obesity Min Jeong Park, Kyung Mook Choi Metabolism.2023

They are involved in reactive oxygen species (such as superoxide anions, hydrogen peroxide, and hydroxyl radicals) and lipid peroxidation product (such as malondialdehyde, 4-hydroxynonenal, F2-isoprostane, leukotriene) detoxification generated during mitochondrial respiration