glutathione s-transferases resistance Frontiers Increase in glutathione S-transferase activity

Dungubat E, Watabe S, Togashi-Kumagai A, Watanabe M, Kobayashi Y, Harada N, et al

As a consequence of damage, direct chemical alteration in the proteins occurs, comprising the creation of disulfide bonds, carbonylation, nitrosylation and glutathionylation

Baseline demographic data of the study groups are displayed in Table 1

1996 Sep;36(18):3003-9

A gene ontology enrichment analysis (ToxoDB) of the 249 proteins decreased in abundance indicated that proteins involved in translation (59 proteins, 6.31-fold enrichment, p-value 2.5 x 10 -33 ), ribosome biogenesis (10 proteins, 3.93-fold enrichment, p-value 1.78 X 10 -4 ), DNA replication (9 proteins, 4.39-fold enrichment, p-value 1.59 x 10 - 4 ), DNA replication initiation (6 proteins, 16.26-fold enrichment, p-value 3.34 x 10 -7 ) and DNA dependent DNA replication (6 proteins, 8.61-fold enrichment, p-value 3.73 x 10 -5 ) were significantly enriched in our dataset

Folgende Anzeichen und Symptome knnen auftreten: Anmie Stoffwechselazidose (Ansammlung von zu viel Sure im Krper) Hufige Infektionen Symptome, die durch Beeintrchtigungen des Gehirns hervorgerufen werden (z.B