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In support of this theory, one paper investigated the possibility of EBV-encoded proteins existing in ME/CFS, such as BRRF1 and BLLF3, and the effects they may have (129), while BLLF3 encodes a dUTPase and is expressed in the early phase of EBV lytic replication (127), EBV (127, 130, 131), and HHV-6 (130) dUTPase proteins has been identified in ME/CFS

OCTN2 has the archetypal MFS fold, with 12 transmembrane helices (TM) organised into two pseudo-symmetric 6-TM bundles (Fig

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