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Also, the male KO mice had an increased CYP1A2 (Part of the P450 enzyme family that are responsible for a large part of detoxification), however this wouldnt really explain the differences seen in Figure 2 (side-note: Ok, this last part was extremely geeky and I try to make this as mainstream as possible

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[DOI] [PubMed] [Google Scholar] 47.Upchurch G.R., Jr., Welch G.N., Fabian A.J., Freedman J.E., Johnson J.L., Keaney J.F., Jr., Loscalzo J

Antioxidant status in acute stroke patients and patients at stroke risk

Adding exogenous prominin 2 to prominin-deficient cells can increase the content of MVBs, confirming that the formation of MVBs is dependent on prominin 2