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121 These chemical modifications play a pivotal role in transforming native peptides into drug-like molecules with improved efficacy and stability, as comprehensively reviewed by Wang et al

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10.1021/acschembio.9b00211 126 SettenR

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Unlike B12 deficiency, which produces recognisable neurological and haematological symptoms, excess vitamin B12 typically remains asymptomatic and is discovered incidentally during routine blood tests