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Although melatonin-dependent mPTP modulation has been widely described with concordant results, related molecular mechanisms have only been proposed

10.1016/j.it.2018.01.005 68 FukaiT.Ushio-FukaiM

Lerner, T

& Jakymiw, A

In a separate ongoing study, a single infusion of CTX320 at 2 mg/kg resulted in a ~94% reduction in Lp(a) levels by day 14, with this reduction maintained until day 224