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However, according to our results, we believe that MPO concentration cannot be used to determine the activation intensity of neutrophils in the body

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Furthermore, unsupervised gut microbiota-based clustering of SLE patients recognized patient subgroups that associated with immune phenotypes and disease activity, which justified the use of microbiota patterns to predict response to therapy (229)

This is a fundamentally different mechanism than finasteride (which blocks DHT production) and potentially a complementary one