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Since previous studies have linked the activation of NRF2 with the repression of lipogenic gene expression 64 , we reasoned that GSH depletion causes oxidation and consequent inactivation of KEAP1 (a repressor of NRF2), thus leading to increased antioxidant and decreased lipogenic gene expression

Mol Endocrinol 11(13):19241933 Hastie PM, Haresign W (2006) Expression of mRNAs encoding insulin-like growth factor (IGF) ligands, IGF receptors and IGF binding proteins during follicular growth and atresia in the ovine ovary throughout the oestrous cycle

doi: 10.1101/gr.2332504 120 TabeL

As previously described, perinatal dietary transitions often induce ruminal dysbiosis, which compromises glucogenic precursor supply and promotes extensive fat mobilization, thereby leading to excessive ketone body production in the liver

doi: 10.1111/bcp.16233 DATA AVAILABILITY STATEMENT Data sharing is not applicable to this article as no new data were created or analyzed in this study

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