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Gastric Cancer Reduction of SLC7A11 expression using pharmacological inhibitors (erastin, Jiyuan Oridonin A derivative a2, levobupivacaine), miRNA (miR-375), long non-coding RNA and siRNA has been shown to inhibit tumor progression through induction of ferroptosis (115118)

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When a CpG island in the promoter region of a gene is methylated, expression of the gene is repressed (it is turned off)

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10.1212/01.WNL.0000167411.93483.A1 101 JunejaM.ShamimU.JoshiA.MathurA.UppiliB.SairamS.et al (2018)