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Phytochemicals influence the expression of neurotrophic factors (NTFs), such as brain-derived and glial cell line-derived NTF (BDNF, GDNF), which are crucial for the viability and function of neurons and if reduced, could promote the development of AD (Siegel and Chauhan, 2000)

Metabolic-stromal hijacking further shapes progression: agmatine stabilizes -catenin via Rnf128 inhibition, activating Wnt-driven tumorigenesis (88)

Tard C, Demailly F, Delval A, Semah F, Defebvre L, Dujardin K, et al

Green-fluorescent protein+ astrocytes attach to -amyloid plaques in an Alzheimer mouse model and are sensitive for clasmatodendrosis

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