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doi: 10.1016/j.bbapap.2017.07.003 251 XuZJinXCaiWZhouMShaoPYangZet al

Despite substantial strides in employing nanoparticles to disrupt ROS for cancer therapy, current strategies continue to grapple with challenges pertaining to efficacy and specificity

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lobata in the Chinese Pharmacopoeia

For example, in colorectal cancer, p53 non-transcriptionally inhibits dipeptidyl peptidase 4 activity to prevent Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-mediated lipid peroxidation and erastin-induced ferroptosis, whereas TP53 deficiency enhances this process [46,47]

405 Other immune cells Experimental evidence indicates that mice lacking MyD88, a critical adapter molecule for TLR signaling, lack ABCs and that pharmacological inhibition of this signaling axis effectively impedes the commitment of B cells to the ABC lineage