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Genetic Factors Some folks might have genetic variants that either accelerate or inhibit alcohol metabolism, thereby impacting their BAC differently

doi: 10.1088/1742-6596/2063/1/012003 177 CismesiaAPNichollsGRPolferNC

The induction of CYP2E1 can stimulate the transport of reduced NADH to the mitochondria, which increases electron leakage from the hepatocyte mitochondrial respiratory chain and ROS generation

In one study, administration of lipoic acid improved survival in a mouse model of ALS (Andreassen 2001b)

Abstract Oxidative stress is one of the key factors that leads to red blood cells (RBCs) aging, and impairs their biomechanics and oxygen delivery