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N-acetyl cysteine inhibits lipopolysaccharide-mediated synthesis of interleukin-1 and tumor necrosis factor- in human periodontal ligament fibroblast cells through nuclear factor-kappa B signaling

Mitochondria are also involved in key cellular functions such as Ca 2 + homeostasis, heme biosynthesis, nutrient metabolism (Hammerman et al., 2004

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Desai N (2012) Challenges in development of nanoparticle-based therapeutics

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To elucidate the possible molecular mechanisms involved in the inhibitory effect of DT-109 on calcification, we measured the protein levels of genes related to vascular calcification in monkeys and showed that DT-109 treatment reduced the protein levels of RUNX family transcription factor 2 (RUNX2) and SRY-box transcription factor 9 (SOX9) (Supplementary Fig