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HIF-1-mediated mitophagy determines ZnO nanoparticle-induced human osteosarcoma cell death both in vitro and in vivo

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In folic acid (FA)-induced AKI, Z-VAD-FMK, an inhibitor of apoptosis, could not reduce the damage to renal tubular epithelial cells, while the ferroptosis inhibitor Fer-1 effectively reduced oxidative stress and renal tubular cell death [136]

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miR-214 sensitizes hepatocytes to ferroptosis To investigate the biological factors responsible for regulating hepatocyte sensitivity to ferroptosis, we focused on the top 25 upregulated miRNAs in the livers of alcoholic hepatitis (AH) patients from the Gene Expression Omnibus database (accession number GSE59492)