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Supplemental Figure S1, Among participants who received durvalumab monotherapy, OS was similar for those who experienced any-grade imAEs versus those who did not (HR, 1.14

A Venn diagram was generated to compare microbial species between groups

Signs of Vitamin B12 deficiency include tiredness, weakness, and pale skin

The applied kinetic models are depicted on the right side of Fig

No pharmacokinetic interaction exists between glutathione (a tripeptide synthesised endogenously and degraded in the small intestine) and tirzepatide (a synthetic peptide that binds GLP-1 and GIP receptors)