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Predicting human oral bioavailability of a compound: development of a novel quantitative structure-bioavailability relationship

doi: 10.1016/s0928-4257(97)89480-6

These findings support the idea that Semax exerts its effects through activation of the hippocampal BDNF/trkB pathway, which plays an important role in overall brain health and cognition

SST-INs sustain synaptic plasticity-dependent pyramidal cell activation, with SST loss correlated to pyramidal destabilisation and reduced motor learning in mice 69