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R is an amino acid selected from isoleucine, leucine and valine

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Pause topical retinoids or other strong skincare products, unless your provider instructs otherwise

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*Correspondence: Tiziana Crepaldi, [email protected] This article was submitted to Signaling, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The peptide doesn't need to stay in your system to keep working because the work it does isn't dependent on its continued presence