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10.1523/JNEUROSCI.5200-13.2014 J

However, the proteins identified as differentially expressed between non-splenectomized -thalassemia/HbE patients and healthy volunteers included a number of cytoskeletal proteins (F-actin -capping protein subunit beta, myosin light polypeptide 6, myosin regulatory light chain 12A, myosin-9, Rho GDP-dissociation inhibitor 2, transgelin-2, PDZ and LIM domain protein 1, and tropomyosin alpha-4 chain) as well as heat shock protein 70 kDa protein, integrin alpha IIb, beta-2-microglobulin, hemoglobin subunit beta, platelet factor 4 (or chemokine (C-X-C motif) and leukocyte elastase inhibitor

This is valid for all indications of aripiprazole, including its use as an antidepressant, and genotyping can be a valuable tool for personalizing treatment and improving outcomes for patients ( Despite the growing recognition of the clinical and economic benefits of optimizing medication use through pharmacogenomics, CYP2D6 genotyping still faces challenges in widespread implementation in clinical practice, particularly due to the complexity of identifying structural variants

& Azevedo, V

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Bachleitner-Hofmann T, Gisslinger B, Grumbeck E, Gisslinger H